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Safety Information

SML1865

Sigma-Aldrich

Rbin-2

≥98% (HPLC)

Synonym(s):

7-Bromo-2-(2-methyl-allylsulfanyl)-9H-1,3,4,9-tetraaza-fluorene, 7-Bromo-3-[(2-methyl-2-propen-1-yl)thio]-5H-1,2,4-Triazino[5,6-b]indole

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About This Item

Empirical Formula (Hill Notation):
C13H11BrN4S
CAS Number:
Molecular Weight:
335.22
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 1 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CC(CSC(N=N1)=NC2=C1C3=C(N2)C=C(Br)C=C3)=C

InChI

1S/C13H11BrN4S/c1-7(2)6-19-13-16-12-11(17-18-13)9-4-3-8(14)5-10(9)15-12/h3-5H,1,6H2,2H3,(H,15,16,18)

InChI key

OVDAOBDZJJZJMY-UHFFFAOYSA-N

Biochem/physiol Actions

Rbin-2 (ribozinoindole-2) is a cell penetrant, potent, selective and reversible inhibitor of Midasin that inhibits eukaryotic ribosome biogenesis. Rbin-2 directly targets AAA+ ATPase Midasin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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