SML1717
RA-2
≥98% (HPLC)
Synonym(s):
1,1′-[1,3-Phenylenebis(methylene)]-3-fluoro-4-hydroxy-benzoic acid ester, 1,3-Phenylenebis(methylene)bis(3-fluoro-4-hydroxybenzoate
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About This Item
Empirical Formula (Hill Notation):
C22H16F2O6
CAS Number:
Molecular Weight:
414.36
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(C1=CC=C(O)C(F)=C1)OCC2=CC=CC(COC(C3=CC(F)=C(O)C=C3)=O)=C2
Biochem/physiol Actions
RA-2 is a selective pan-negative-gating modulator of KCa2/3 channels that potently inhibits both ex vivo and in vivo human KCa3.1 and all three human KCa2 channels subtypes. RA-2 right-shifts the KCa3.1 concentration-response curve for Ca2+-activation.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Regulatory Information
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