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SML1647

Sigma-Aldrich

Epiblastin A

≥98% (HPLC)

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Synonym(s):
2,4,7-Triamino-6-(m-chlorophenyl)-pteridine, 6-(3-Chlorophenyl)-2,4,7-pteridinetriamine
Empirical Formula (Hill Notation):
C12H10ClN7
CAS Number:
Molecular Weight:
287.71
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 1 mg/mL, clear (warmed)

storage temp.

room temp

SMILES string

NC1=NC(N)=C2C(N=C(N)C(C3=CC=CC(Cl)=C3)=N2)=N1

InChI

1S/C12H10ClN7/c13-6-3-1-2-5(4-6)7-9(14)18-11-8(17-7)10(15)19-12(16)20-11/h1-4H,(H6,14,15,16,18,19,20)

InChI key

ZWNKKZSRANLVEW-UHFFFAOYSA-N

Biochem/physiol Actions

Epiblastin A is triamterene derivative that potently induces reprograming of epiblast stem cells (EpiSC) into embryonic stem cells (ESC). Epiblastin A is a potent reversible inhibitor of casein kinase 1 (CK1) α, δ, and ε that binds to ATP-binding site.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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