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SML1526

Sigma-Aldrich

Eltoprazine hydrochloride

≥98% (HPLC)

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Synonym(s):
1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
Empirical Formula (Hill Notation):
C12H16N2O2 · HCl
CAS Number:
98206-09-8
Molecular Weight:
256.73
MDL number:
MFCD06245586
UNSPSC Code:
12352202
PubChem Substance ID:
329825943
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 10 mg/mL, clear

storage temp.

room temp

SMILES string

[H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1

InChI

1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H

InChI key

JFSOSUNPIXJCIX-UHFFFAOYSA-N

Related Categories

General description

Eltoprazine, a serotonergic agent, possesses specific anti-aggressive (serenic) properties in various animal models without triggering sedation, motor disturbances, or muscle relaxation.

Biochem/physiol Actions

Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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