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SML1483

Sigma-Aldrich

Ogerin negative control

≥98% (HPLC)

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Synonym(s):
3-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol
Empirical Formula (Hill Notation):
C17H17N5O
CAS Number:
Molecular Weight:
307.35
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

NC1=NC(C2=CC(CO)=CC=C2)=NC(NCC3=CC=CC=C3)=N1

InChI

1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)

InChI key

RVKAHYFWSKSSQQ-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.

Recommended products

The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here.

related product

Product No.
Description
Pricing

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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