All Photos(1)
7,7a-Dihydro-7-(hydroxyimino)-N-phenyl-benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide
C17H14N2O3
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Quality Level
Assay
≥97% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(NC1=CC=CC=C1)C2(C/3C2)OC4=C(C=CC=C4)C3=N/O
InChI
1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15+
InChI key
FPXPIEZPAXSELW-XDJHFCHBSA-N
Biochem/physiol Actions
PHCCC is a positive allosteric modulator (PAM) at the mGluR4 subtype that exhibits anxiolytic and anti-Parkinsonian effects in animal models. PHCCC is a potent group I metabotropic glutamate receptor antagonist.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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