All Photos(1)
S-(2-Boronoethyl)-L-cysteine, S-(2-Boronoethyl)-L-cysteine hydrochloride
C5H12BNO4S · xHCl
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
OB(O)CCSC[C@H](N)C(O)=O.C
InChI
1S/C5H12BNO4S.CH4/c7-4(5(8)9)3-12-2-1-6(10)11;/h4,10-11H,1-3,7H2,(H,8,9);1H4/t4-;/m0./s1
InChI key
IMYJQAMXIIYUIH-WCCKRBBISA-N
Biochem/physiol Actions
BEC (S-(2-boronoethyl)-l-cysteine) is a potent and specific arginase inhibitor that restores flow-induced responses in arterioles from diabetic rats.
BEC is a boronic analog of L-arginine, and L-cysteine. It competitively inhibits both arginase I and II. BEC does not directly affect nitric oxide synthase.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Amino Acids in Human Nutrition and Health, 62-62 (2012)
Expert review of molecular diagnostics, 18(7), 675-683 (2018-05-01)
Despite improvement in overall response due to the introduction of the first-in-class proteasome inhibitor bortezomib (btz), multiple myeloma (MM) is still an incurable disease due to the immune-suppressive bone marrow (BM) environment. Thus, the authors aimed to identify the role
Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension
American Journal of Physiology. Lung Cellular and Molecular Physiology, 288(4), R1057-R1062 (2005)
Cellular and molecular life sciences : CMLS, 78(2), 661-673 (2020-04-25)
This study shows that melanoma-associated fibroblasts (MAFs) suppress cytotoxic T lymphocyte (CTL) activity and reveals a pivotal role played by arginase in this phenomenon. MAFs and normal dermal fibroblasts (DFs) were isolated from surgically resected melanomas and identified as Melan-A-/gp100-/FAP+ cells.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service