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SML1283

Sigma-Aldrich

Cilastatin sodium Ready Made Solution

50 mg/mL in DMSO/H2O, 1:1

Synonym(s):

((Z)-7-[(2R)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-{[(1S)-2,2-dimethylcyclopropanecarbonyl]amino}hept-2-enoic acid

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About This Item

Empirical Formula (Hill Notation):
C16H26N2O5S
CAS Number:
81129-83-1
Molecular Weight:
358.45
UNSPSC Code:
12352200
NACRES:
NA.77

form

liquid (1:1 DMSO:H2O)

Quality Level

200

concentration

50 mg/mL in DMSO/H2O, 1:1

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11-;/m1./s1

InChI key

QXPBTTUOVWMPJN-VQAYNFQASA-M

Biochem/physiol Actions

Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases. By this action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.

WGK

WGK 3

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