Skip to Content
Merck
CN
All Photos(1)

Key Documents

View All Documentation

Safety Information

SML1273

Sigma-Aldrich

ML347

≥98% (HPLC)

Synonym(s):

5-[6-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline, LDN-193719, VU0469381

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H16N4O
CAS Number:
1062368-49-3
Molecular Weight:
352.39
MDL number:
MFCD28099805
UNSPSC Code:
12352200
PubChem Substance ID:
329825760

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 1 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

COC(C=C1)=CC=C1C2=CN3N=CC(C4=CC=CC5=C4C=CC=N5)=C3N=C2

InChI

1S/C22H16N4O/c1-27-17-9-7-15(8-10-17)16-12-24-22-20(13-25-26(22)14-16)18-4-2-6-21-19(18)5-3-11-23-21/h2-14H,1H3

InChI key

FVRYPYDPKSZGNS-UHFFFAOYSA-N

Biochem/physiol Actions

ML347 is a derivative of dorsomorphin that is a highly selective antagonist of BMP receptor isotypes ALK1 and ALK2 (IC50 values = 46 and 32 nM, respectively). ML347 has little effect on other ALK isoforms, including ALK3 (IC50 = 10 μM).
ML347 is a highly selective antagonist of BMP receptor isotypes ALK1 and ALK2.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
065M4751V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service