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SML1263

Sigma-Aldrich

Arylquin 1

≥98% (HPLC)

Synonym(s):

3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine)

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About This Item

Empirical Formula (Hill Notation):
C17H16FN3
CAS Number:
1630743-73-5
Molecular Weight:
281.33
MDL number:
MFCD28580129
UNSPSC Code:
12352200
PubChem Substance ID:
329825755
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

, white to yellow to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F

InChI

1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20)

InChI key

RHAQINSYYSNKKI-UHFFFAOYSA-N

Biochem/physiol Actions

Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.
Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000123189
035M4608V

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