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Safety Information

SML1041

Sigma-Aldrich

Atreleuton

≥98% (HPLC)

Synonym(s):

(R)-N-(3-(5-(4-Fluorophenylmethyl)thien-2-yl)-1-methyl-2-propynyl)-N-hydroxyurea, A8576, ABT 761, VIA-2291

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About This Item

Empirical Formula (Hill Notation):
C16H15FN2O2S
CAS Number:
Molecular Weight:
318.37
UNSPSC Code:
51111800
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +40 to +50°, c = 1 in methanol

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

Fc1ccc(cc1)Cc2[s]c(cc2)C#C[C@H](N(O)C(=O)N)C

InChI

1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m1/s1

InChI key

MMSNEKOTSJRTRI-LLVKDONJSA-N

Biochem/physiol Actions

Atreleuton is a reversible 5-lipoxygenase inhibitor. Atreleuton exhibits potent and selective inhibition of leukotriene formation both in vitro and in vivo.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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