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SML0988

Sigma-Aldrich

CCCI-01

≥98% (HPLC)

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Synonym(s):
5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide
Empirical Formula (Hill Notation):
C11H9N3O4
CAS Number:
215778-97-5
Molecular Weight:
247.21
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C11H9N3O4/c15-11(9-3-4-10(18-9)14(16)17)13-7-8-2-1-5-12-6-8/h1-6H,7H2,(H,13,15)

InChI key

OBZHOVWNZIVCCZ-UHFFFAOYSA-N

Biochem/physiol Actions

CCCI-01 induces the fomation of multipolar spindles in cancer cells containing multiple, or supernumerary centromeres. CCCI-01 leads to centromere declustering, disruption of cell cycle and apoptsis in BT-549 breast cancer cells without affecting bipolar spindles in normal primary human mammary epithelial cells.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

Bioactive Molecules for Apoptosis

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

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