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Merck
CN

SML0972

ORM-10103

≥98% (HPLC)

Synonym(s):

2-[(3,4-Dihydro-2-phenyl-2H-1-benzopyran-6-yl)oxy]-5-nitro-pyridine

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About This Item

Empirical Formula (Hill Notation):
C20H16N2O4
CAS Number:
488847-28-5
Molecular Weight:
348.35
UNSPSC Code:
12352200
NACRES:
NA.77

Key Documents

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SMILES string

[N+](=O)([O-])c1cnc(cc1)Oc2cc3c(cc2)OC(CC3)c4ccccc4

InChI

1S/C20H16N2O4/c23-22(24)16-7-11-20(21-13-16)25-17-8-10-19-15(12-17)6-9-18(26-19)14-4-2-1-3-5-14/h1-5,7-8,10-13,18H,6,9H2

InChI key

GZONLGPIHCCJOI-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

Quality Level

100

Related Categories

Biochem/physiol Actions

ORM-10103 is a potent, specific inhibitor of the Na(+)/Ca(2+) exchanger, NCX.
ORM-10103 is a potent, specific inhibitor of the Na(+)/Ca(2+) exchanger, NCX. The compound ORM-10103 inhibits both inward and outward NCX currents with IC50 values of 780 nM, and 960 nM, respectively. ORM-10103 blocks induced arrhythmias in canine cardiac tissue.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H413

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000189711
0000189711
0000065340
0000064942
0000065341

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