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SML0931

Carbimazole

Name: Carbimazole
Brand: SIGMA

≥98% (HPLC)

Synonym(s):

1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline, 1-Methyl-3-carbethoxy-2-thioglyoxalone, 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid ethyl ester, Athyromazole, Carbethoxymethimazole, Carbimazol, Ethyl 3-methyl-2-thioimidazoline-1-carboxylate

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About This Item

Empirical Formula (Hill Notation):

C₇H₁₀N₂O₂S

CAS Number:

22232-54-8

Molecular Weight:

186.23

UNSPSC Code:

12352200

EC Number:

244-854-4

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

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Properties

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

S=[c]1[n](cc[n]1C(=O)OCC)C

InChI

1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3

InChI key

CFOYWRHIYXMDOT-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase.

Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase. Carbimazole is used to treat hyperthyroidism. Also, carbimazole induces phosphorylation of eukaryotic elongation factor eEF2.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Articles

DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Papillary carcinoma masquerading as clinically toxic adenoma in very young children.

Nishikant Damle et al.

Journal of pediatric endocrinology & metabolism : JPEM, 24(11-12), 1051-1054 (2012-02-09)

Autonomously functioning thyroid nodules (AFTN) are extremely rare in children. Malignancy may be rarely found in hyperfunctioning 'hot' nodules in adults. However, there are limited reports of AFTNs in young children presenting as or developing malignancy in future. We report

An online survey to determine owner experiences and opinions on the management of their hyperthyroid cats using oral anti-thyroid medications.

Sarah M A Caney

Journal of feline medicine and surgery, 15(6), 494-502 (2013-04-18)

Hyperthyroidism is the most common feline endocrinopathy. Treatment options comprise anti-thyroid medication, iodine-restricted diet, surgical thyroidectomy and radioiodine. One hundred and eleven owners of hyperthyroid cats completed a detailed survey asking about their experiences and views on the management of

Which antithyroid drug regimen in paediatric Graves' disease?

Daniel Schenk et al.

Clinical endocrinology, 77(6), 806-807 (2012-07-24)

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Global Trade Item Number

SKU	GTIN
SML0931-10MG	04061832724171
SML0931-50MG	04061832724188

Key Documents

Carbimazole

≥98% (HPLC)

Select a Size

About This Item

Quality Level

assay

form

color

solubility

storage temp.

SMILES string

InChI

InChI key

Biochem/physiol Actions

Still not finding the right product?

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

Documentation

Certificates of Analysis (COA)

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Articles

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Global Trade Item Number