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Safety Information

SML0878

Sigma-Aldrich

BRD9757

≥98% (HPLC)

Synonym(s):

N-Hydroxy-1-cyclopentene-1-carboxamide

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About This Item

Empirical Formula (Hill Notation):
C6H9NO2
CAS Number:
1423058-85-8
Molecular Weight:
127.14
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

BRD9757 is a selective inhbitor of the histone deacetylase HDAC6 (IC50 = 30 nM). BRD9757 dose dependently increases levels of acetylated α-tubulin in HeLa cells, with no affect on H3 acetylation.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319,H412

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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Articles

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

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