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Safety Information

SML0792

Sigma-Aldrich

JW480

≥98% (HPLC)

Synonym(s):

2-Isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate, JW 480

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About This Item

Empirical Formula (Hill Notation):
C22H23NO2
CAS Number:
1354359-53-7
Molecular Weight:
333.42
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

N(CCc2cc3c(cc2)cccc3)C(=O)Oc1c(cccc1)C(C)C

InChI

1S/C22H23NO2/c1-16(2)20-9-5-6-10-21(20)25-22(24)23-14-13-17-11-12-18-7-3-4-8-19(18)15-17/h3-12,15-16H,13-14H2,1-2H3,(H,23,24)

InChI key

PCNJGBMWAZRVEA-UHFFFAOYSA-N

Biochem/physiol Actions

JW480 is a highly potent and selective inhibitor of KIAA1363.
JW480 is a highly potent and selective inhibitor of KIAA1363. JW480 reduce MAGEs and impair the migration, invasion, survival, and in vivo tumor growth of human prostate cancer cell lines.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000151625
0000151625
0000134119
083M4603V

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Yuchuan Li et al.
Cancer cell international, 23(1), 276-276 (2023-11-18)
Despite therapeutic advances, the prognosis of pancreatic ductal adenocarcinoma (PDAC) remains extremely poor. Metabolic reprogramming is increasingly recognized as a key contributor to tumor progression and therapy resistance in PDAC. One of the main metabolic changes essential for tumor growth

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