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About This Item
Empirical Formula (Hill Notation):
C16H22N2O2S · HCl
CAS Number:
Molecular Weight:
342.88
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder or crystals
color
white to beige
solubility
H2O: 15 mg/mL, clear
storage temp.
room temp
SMILES string
[S](=O)(=O)(NCCCCCCN)c1c2c(ccc1)cccc2.Cl
InChI
1S/C16H22N2O2S.ClH/c17-12-5-1-2-6-13-18-21(19,20)16-11-7-9-14-8-3-4-10-15(14)16;/h3-4,7-11,18H,1-2,5-6,12-13,17H2;1H
InChI key
HOCSVIGHWPLMFC-UHFFFAOYSA-N
Biochem/physiol Actions
N-(6-Aminohexyl)-1-naphthalenesulfonamide (W-5) is a cell permeable calmodulin antagonist that binds directly to the enzyme.
N-(6-Aminohexyl)-1-naphthalenesulfonamide (W-5) is a cell permeable calmodulin antagonist.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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S Suzuki et al.
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R M Bernal et al.
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P Menè et al.
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Sustained Ca2+ influx follows discharge of intracellularly stored Ca2+ in a variety of cell types previously equilibrated in Ca(2+)-free media, including cultured human mesangial cells. This Ca2+ influx pathway has been referred to as capacitative Ca2+ entry or Ca2+ release-activated
A Takahashi et al.
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The mouse intestinal neuroendocrine tumor cell line STC-1 secretes cholecystokinin (CCK) and other hormones. We investigated the role of Ca2+, calmodulin (CaM), and protein kinase C (PKC) in the regulation of CCK release from STC-1 cells. Phorbol 12-myristate 13-acetate (TPA)
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