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Safety Information

SML0604

Sigma-Aldrich

SB-399885 hydrochloride

≥98% (HPLC)

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Synonym(s):
N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-benzenesulfonamide hydrochloride
Empirical Formula (Hill Notation):
C18H21Cl2N3O4S · HCl
CAS Number:
402713-81-9
Molecular Weight:
482.81
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 15 mg/mL, clear

storage temp.

room temp

InChI

1S/C18H21Cl2N3O4S/c1-26-17-4-3-13(11-16(17)23-7-5-21-6-8-23)28(24,25)22-15-10-12(19)9-14(20)18(15)27-2/h3-4,9-11,21-22H,5-8H2,1-2H3

InChI key

ATKZKAYWARYLBW-UHFFFAOYSA-N

Biochem/physiol Actions

SB-399885 is a potent, selective, and orally active 5-HT6 receptor antagonist with greater than 200 fold selectivity over other 5-HT receptors. SB-399885 is brain penetrant and displays antidepressant and anxiolytic activity in rodent models.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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