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Safety Information

SML0507

Sigma-Aldrich

NPC26

≥98% (HPLC)

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Synonym(s):
4,5,6,7-Tetrahydro-5,5,7,7-tetramethyl-2-[[(5-nitro-2-thienyl)carbonyl]amino]-thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester, NPC-26
Empirical Formula (Hill Notation):
C19H23N3O5S2
CAS Number:
864860-32-2
Molecular Weight:
437.53
MDL number:
MFCD04428321
UNSPSC Code:
12352200
PubChem Substance ID:
329825516
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

light orange to dark orange

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CCOC(=O)c1c2CC(C)(C)NC(C)(C)c2sc1NC(=O)c3ccc(s3)[N+]([O-])=O

InChI

1S/C19H23N3O5S2/c1-6-27-17(24)13-10-9-18(2,3)21-19(4,5)14(10)29-16(13)20-15(23)11-7-8-12(28-11)22(25)26/h7-8,21H,6,9H2,1-5H3,(H,20,23)

InChI key

DWGSXNATVAGHKZ-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

NPC26 induces mitochondrial fragmentation and cell death in RAS expressing cells, similar to erastin. The effects of NPC26 are independent of ROS scavengers, which can block cell death induced by erastin.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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