Skip to Content

尊敬的客户：

目前国际形势复杂多变，关税政策尚不明朗，这可能对我们的产品价格产生一定影响。在此情况下，我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性，如果您选择在此期间下单，我们将保留根据实际情况调整价格的权利。同时，我们也理解市场变化可能给您带来的困扰，因此如果在订单实际发货前因关税政策变动导致价格出现较大波动，默克将与您进行协商讨论并视情况对订单进行调整或取消。

Merck
CN
All Photos(1)

Key Documents

View All Documentation

SML0494

Sigma-Aldrich

VU0361737

≥98% (HPLC)

Synonym(s):

CID-44191096, ML128, N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C13H11ClN2O2
CAS Number:
1161205-04-4
Molecular Weight:
262.69
MDL number:
MFCD16618402
UNSPSC Code:
12352200
PubChem Substance ID:
329825444
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

100

Assay

≥98% (HPLC)

form

film

color

white

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

COc1cc(NC(=O)c2ccccn2)ccc1Cl

InChI

1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)

InChI key

ARYUXFNGXHNNDM-UHFFFAOYSA-N

Biochem/physiol Actions

VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM).

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    092M4618V

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Articles

    Glutamate Receptors (G Protein Family)

    Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service