SML0337
S-Allyl-L-cysteine
≥98% (HPLC), antioxidant, powder
Synonym(s):
L-Deoxyalliin, S-allyl-cysteine, S-allylcysteine, SAC
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About This Item
Empirical Formula (Hill Notation):
C6H11NO2S
CAS Number:
Molecular Weight:
161.22
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Product Name
S-Allyl-L-cysteine, ≥98% (HPLC)
SMILES string
N[C@@H](CSCC=C)C(O)=O
InChI
1S/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1
InChI key
ZFAHNWWNDFHPOH-YFKPBYRVSA-N
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D -8 to -15°, c = 1 in H2O
color
white to beige
solubility
H2O: >10 mg/mL
storage temp.
−20°C
Quality Level
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General description
S-Allyl-L-cysteine has anti-inflammatory properties. It inhibits prooxidant enzymes and chelates metals. S-Allyl-L-cysteine exhibits hypoglycemic and cholesterol-lowering effects. It prevents apoptosis, lowers the activity of inducible nitric oxide synthase and blocks nuclear factor kappa B activity.
Biochem/physiol Actions
S-allyl-L-cysteine is a sulfur containing amino acid found in garlic with antioxidant, anti-cancer, antihepatotoxic, neuroprotective and neurotrophic activity.
S-allyl-L-cysteine is a sulfur containing amino acid found in garlic with antioxidant, anti-cancer, antihepatotoxic, neuroprotective and neurotrophic activity. S-allyl-L-cysteine has potent activity in several animal models of ischemic injury and Alzhemer′s disease.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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J Yu et al.
Placenta, 33(6), 487-494 (2012-03-13)
Preeclampsia (PE) is a major cause of fetal growth restriction and perinatal mortality, which involves oxidative stress and vasodilator signaling disorder. S-allyl-L-cysteine (SAC) is one of the most abundant compounds in garlic extracts, and possesses several biological activities. This research
Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease: Prevention and Therapy (2014)
Patricia Rojas et al.
The Journal of nutritional biochemistry, 22(10), 937-944 (2010-12-31)
S-Allylcysteine (SAC), the most abundant organosulfur compound in aged garlic extract, has multifunctional activity via different mechanisms and neuroprotective effects that are exerted probably via its antioxidant or free radical scavenger action. The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse has been the most widely
Hayate Javed et al.
Brain research, 1389, 133-142 (2011-03-08)
S-allyl cysteine (SAC), a sulfur containing amino acid derived from garlic, has been reported to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was designed to examine the pre-treatment effects of SAC on cognitive deficits and oxidative damage in
Kevin T P Ng et al.
PloS one, 7(2), e31655-e31655 (2012-03-06)
Hepatocellular carcinoma (HCC) is highly malignant and metastatic. Currently, there is no effective chemotherapy for patients with advanced HCC leading to an urgent need to seek for novel therapeutic options. We aimed to investigate the effect of a garlic derivative
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