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Merck
CN
All Photos(1)

Key Documents

Safety Information

SML0298

Sigma-Aldrich

PSNCBAM-1

≥98% (HPLC)

Synonym(s):

N-(4-Chlorophenyl)-N′-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]-urea

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1 KG
CN¥407.32
5 KG
CN¥2,582.22

CN¥407.32

List PriceCN¥1,357.73Save 70%

Estimated to ship onJune 25, 2025Details


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1 KG
CN¥407.32
5 KG
CN¥2,582.22

About This Item

Empirical Formula (Hill Notation):
C22H21ClN4O
CAS Number:
Molecular Weight:
392.88
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

CN¥407.32

List PriceCN¥1,357.73Save 70%

Estimated to ship onJune 25, 2025Details


Request a Bulk Order

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

Clc1ccc(NC(=O)Nc2cccc(c2)-c3cccc(n3)N4CCCC4)cc1

InChI

1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)

InChI key

HDAYFSFWIPRJSO-UHFFFAOYSA-N

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T046730610H100
application(s)

clinical testing

application(s)

clinical testing

application(s)

-

application(s)

clinical testing
clinical testing

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

form

liquid

form

liquid

form

solution

form

liquid

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

300

grade

certified reference material

grade

certified reference material

grade

-

grade

certified reference material

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Biochem/physiol Actions

PSNCBAM-1 is an allosteric, non-competitive antagonist of CB-1.
PSNCBAM-1 is an allosteric, non-competitive antagonist of CB-1. The compound blocks the effects of WIN 55212-2 and CP55940, and reduces food intake and weight gain in rats.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Thomas F Gamage et al.
    Neuropharmacology, 125, 365-375 (2017-08-15)
    While allosteric modulators of the cannabinoid type-1 receptor (CB

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