SML0254
4-MDM
≥98% (HPLC)
Synonym(s):
4-Methoxydiphenylmethane
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About This Item
Empirical Formula (Hill Notation):
C14H14O
CAS Number:
Molecular Weight:
198.26
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C14H14O/c1-15-14-9-7-13(8-10-14)11-12-5-3-2-4-6-12/h2-10H,11H2,1H3
SMILES string
COc1ccc(Cc2ccccc2)cc1
InChI key
GQLYCRTUQGSDSM-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
oil (Low melting solid)
color
colorless
storage temp.
room temp
Biochem/physiol Actions
4-MDM augments the aminopeptidase activity of LTA4 hydrolase without affecting the conversion of LTA4 to LTB4.
4-MDM augments the aminopeptidase activity of LTA4 hydrolase without affecting the conversion of LTA4 to LTB4. Treatment with 4-MDM protects mouse lungs from intranasal elastase-induced pulmonary emphysema.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Eye Dam. 1 - Skin Irrit. 2
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Shin Numao et al.
Scientific reports, 7(1), 13591-13591 (2017-10-21)
Leukotriene A4 Hydrolase (LTA4H) is a bifunctional zinc metalloenzyme that comprises both epoxide hydrolase and aminopeptidase activity, exerted by two overlapping catalytic sites. The epoxide hydrolase function of the enzyme catalyzes the biosynthesis of the pro-inflammatory lipid mediator leukotriene (LT)
Caroline M Low et al.
Scientific reports, 7, 44449-44449 (2017-03-18)
The pro-inflammatory mediator leukotriene B
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