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Key Documents

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Safety Information

SML0247

Sigma-Aldrich

Rizatriptan benzoate salt

≥98% (HPLC)

Synonym(s):

MK-462, N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt

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5 MG
¥1,978.95
25 MG
¥6,372.41

¥1,978.95

Please contact Customer Service for Availability
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5 MG
¥1,978.95
25 MG
¥6,372.41

About This Item

Empirical Formula (Hill Notation):
C15H19N5 · C7H6O2
CAS Number:
145202-66-0
Molecular Weight:
391.47
MDL number:
MFCD00866224
UNSPSC Code:
12352200
PubChem Substance ID:
329825257
NACRES:
NA.77

¥1,978.95

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: ≥5 mg/mL

storage temp.

room temp

SMILES string

OC(=O)c1ccccc1.CN(C)CCc2c[nH]c3ccc(Cn4cncn4)cc23

InChI

1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)

InChI key

JPRXYLQNJJVCMZ-UHFFFAOYSA-N

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MXRPWRSPUK

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MXRPWRSPBR

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packaging

pkg of 1 ea

packaging

pkg of 1 ea

packaging

pkg of 1 ea

packaging

pkg of 1 ea

manufacturer/tradename

Milliflex®

manufacturer/tradename

Milliflex®

manufacturer/tradename

Milliflex®

manufacturer/tradename

Milliflex®

technique(s)

Rapid Sterility Testing: suitable

technique(s)

Rapid Sterility Testing: suitable

technique(s)

Rapid Sterility Testing: suitable

technique(s)

Rapid Sterility Testing: suitable

application(s)

bioburden testing
pharmaceutical
sterility testing

application(s)

bioburden testing
pharmaceutical
sterility testing

application(s)

bioburden testing
pharmaceutical
sterility testing

application(s)

bioburden testing
pharmaceutical
sterility testing

Biochem/physiol Actions

Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine.
Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360

Precautionary Statements

P201 - P308 + P313

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

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    Certificates of Analysis (COA)

    Lot/Batch Number
    033M4734V
    022M4725V

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    Piero Barbanti et al.
    The journal of headache and pain, 13(5), 407-414 (2012-03-31)
    The objective and background is to confirm in a double-blind, placebo-controlled study the high triptan response rates we had previously reported in an open study in migraine patients with unilateral cranial autonomic symptoms. In this randomized, double-blind, placebo-controlled study 80
    Thomas Müller et al.
    Clinical neuropharmacology, 34(6), 206-209 (2011-10-15)
    Triptans and analgetic nonsteroidal inflammatory drugs reduce acute pain syndromes in migraine. A further treatment option for an acute headache attack in patients with migraine may be the application of cyclooxygenase-2-specific inhibitors, as they have anti-inflammatory and analgesic properties. The
    Amelia M Avachat et al.
    Carbohydrate polymers, 91(2), 537-542 (2012-11-06)
    Mucoadhesive buccal films were developed using tamarind seed xyloglucan (TSX) as novel mucoadhesive polysaccharide polymer for systemic delivery of rizatriptan benzoate through buccal route. Formulations were prepared based on 3(2) factorial design with concentrations of TSX and carbopol 934P (CP)
    Types of colitis based on histology.
    Muhammed Sherid et al.
    Disease-a-month : DM, 57(9), 457-489 (2011-09-29)
    Anthony J Rodgers et al.
    Headache, 51(3), 356-368 (2010-11-03)
    To examine total migraine freedom (TMF), defined as pain freedom and absence of associated symptoms, using rizatriptan clinical trial data and to explore advantages of TMF as a single primary composite efficacy endpoint. The FDA has set a higher regulatory
    View All Related Papers

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