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SML0154

Sigma-Aldrich

SPV-106

≥98% (HPLC)

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Synonym(s):
2-Pentadecylidene-Propanedioic acid 1,3-diethyl ester, Pentadecylidenemalonate 1b
Empirical Formula (Hill Notation):
C22H40O4
CAS Number:
1036939-38-4
Molecular Weight:
368.55
MDL number:
MFCD20527327
UNSPSC Code:
12352200
PubChem Substance ID:
329825202
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

oil

color

colorless

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCC\C=C(\C(=O)OCC)C(=O)OCC

InChI

1S/C22H40O4/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21(23)25-5-2)22(24)26-6-3/h19H,4-18H2,1-3H3

InChI key

APIJHPAXMCKJBY-UHFFFAOYSA-N

Biochem/physiol Actions

SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. The compound inhibits the activity of p300/CBP, but potentiates p300/CBP-associated factor (PCAF) activity. SPV106 also induces S-phase cell cycle arrest and apoptosis in U937 cells.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Discover Bioactive Small Molecules for Gene Regulation

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