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Safety Information

SML0144

Sigma-Aldrich

2002-H20

≥98% (HPLC)

Synonym(s):

4-amino-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-benzamide

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About This Item

Empirical Formula (Hill Notation):
C20H15N3O3
CAS Number:
Molecular Weight:
345.35
MDL number:
UNSPSC Code:
12352203
PubChem Substance ID:
NACRES:
NA.25

Assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

DMSO: ≥15 mg/mL

storage temp.

2-8°C

SMILES string

Nc1ccc(cc1)C(=O)Nc2ccc(O)c(c2)-c3nc4ccccc4o3

InChI

1S/C20H15N3O3/c21-13-7-5-12(6-8-13)19(25)22-14-9-10-17(24)15(11-14)20-23-16-3-1-2-4-18(16)26-20/h1-11,24H,21H2,(H,22,25)

InChI key

NVVIQGMTHCUMFT-UHFFFAOYSA-N

Biochem/physiol Actions

2002-H20 is an Alheimer′s Aβ peptide binder. It inhibits Aβ-induced death of PC12 cells, reducing the amount of toxic oligomer by enhancing fibril formation.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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