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Merck
CN

SML0138

Levalbuterol hydrochloride

≥98% (HPLC)

Synonym(s):

(R)-salbutamol hydrochloride, Levosalbutamol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H21NO3 · HCl
CAS Number:
50293-90-8
Molecular Weight:
275.77
NACRES:
NA.77
PubChem Substance ID:
329825186
UNSPSC Code:
12352200
MDL number:
MFCD08067728

Key Documents

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Product Name

Levalbuterol hydrochloride, ≥98% (HPLC)

color

white to tan

InChI

1S/C13H21NO3.ClH/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;/h4-6,12,14-17H,7-8H2,1-3H3;1H/t12-;/m0./s1

SMILES string

Cl.CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1

InChI key

OWNWYCOLFIFTLK-YDALLXLXSA-N

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -25 to -35°, c = 0.1 in H2O

storage condition

desiccated

solubility

H2O: ≥15 mg/mL

storage temp.

2-8°C

Quality Level

100

Gene Information

human ... ADRB2(154)

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Application

Levalbuterol hydrochloride may be used in β2-adrenergic-mediated cell signaling studies.

Biochem/physiol Actions

β-Adrenergic Agonist; Bronchodilator; more active isomer of albutamol
Levalbuterol (levosalbutamol) is the more active isomer of albuterol. Levalbuterol is a β-adrenergic agonist; a bronchodilator used clinically to treat asthma and COPD..
Levalbuterol is (R)-albuterol that exhibits bronchodilator effect and is more effective than racemic albuterol for the treatment of exacerbation of asthma in pediatric populations.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000487101
0000487101
0000200322
0000200324
091M4729V

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Madhu D Hardasmalani et al.
Pediatric emergency care, 21(7), 415-419 (2005-07-20)
To compare levalbuterol and racemic albuterol for the treatment of acute exacerbation of asthma in pediatric population. Prospective, double-blind, randomized research trial in a pediatric emergency department of an urban tertiary care hospital. Children 5 to 21 years with a

Articles

β-Adrenoceptors

β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.

β-肾上腺素能受体

β-肾上腺素受体可被去甲肾上腺素或肾上腺素激活。详细了解β-肾上腺素受体在蛋白质表达、细胞信号传导和代谢研究中的作用。

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