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SMB01081

Sigma-Aldrich

Ethyl 3,4-Dihydroxycinnamate

≥90% (LC/MS-ELSD)

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Synonym(s):
3,4-Dihydroxycinnamic acid ethyl ester, Ethyl caffeate, ethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Empirical Formula (Hill Notation):
C11H12O4
CAS Number:
Molecular Weight:
208.21
MDL number:
UNSPSC Code:
12352205
NACRES:
NA.25

biological source

plant

Assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

208.21

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C11H12O4/c1-2-15-11(14)6-4-8-3-5-9(12)10(13)7-8/h3-7,12-13H,2H2,1H3/b6-4+

InChI key

WDKYDMULARNCIS-GQCTYLIASA-N

General description

Ethyl dihydroxycinnamate, or ethyl caffeate, is a sesquiterpene lactone classified as a caffeic acid derivative. It naturally occurs in plants like coffee, tea, and fruits. This plant metabolite boasts diverse biological properties, including anti-oxidative, anti-inflammatory, anti-cancer, anti-diabetic, neuroprotective, and antimicrobial effects.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Ethyl dihydroxycinnamate exhibits potent cytotoxicity, inhibits COX-2 and P-hydroxybenzoic acid, both involved in inflammation and cytokine synthesis. It demonstrates antibacterial efficacy against MRSA and Bacillus subtilis and inhibits cancer cell growth, countering tumor formation.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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