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SMB01016

Sigma-Aldrich

Pomolic acid

≥90% (LC/MS-ELSD)

Synonym(s):

19α-Hydroxyursolic acid, Benthamic acid, Randialic acid A

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About This Item

Empirical Formula (Hill Notation):
C30H48O4
CAS Number:
13849-91-7
Molecular Weight:
472.70
MDL number:
MFCD21333659
UNSPSC Code:
12352205
NACRES:
NA.25

biological source

plant

Assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

472.7

solubility

water: slightly soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C30H48O4/c1-18-10-15-30(24(32)33)17-16-27(5)19(23(30)29(18,7)34)8-9-21-26(4)13-12-22(31)25(2,3)20(26)11-14-28(21,27)6/h8,18,20-23,31,34H,9-17H2,1-7H3,(H,32,33)/t18-,20+,21-,22+,23-,26+,27-,28-,29-,30+/m1/s1

InChI key

ZZTYPLSBNNGEIS-OPAXANQDSA-N

Related Categories

General description

Pomolic acid, a pentacyclic triterpene, is a bioactive natural compound commonly derived from plants such as Euscaphis japonica, Centella asiatica, Picramnia sellowii, and Cecropia pachystachya. Current research suggests that this metabolite acts as an inhibitor and may exhibit diverse biological activities, including anticancer, anti-inflammatory, antiviral, apoptotic, and antihypertensive properties.
Natural product derived from plant source.

Application

Pomolic acid is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Pomolic acid is highly effective in inhibiting cell growth and inducing apoptosis.

Features and Benefits

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Guillermo Schinella et al.
Planta medica, 74(3), 215-220 (2008-02-09)
The dichloromethane extract and pomolic acid ( 5) obtained from leaves of Cecropia pachystachya both reduced carrageenan-induced paw oedema in mice. Interestingly, while the triterpenoid inhibited the in vivo production of interleukin-1beta by 39 %, it had no effect on
Phuong Thien Thuong et al.
Biological & pharmaceutical bulletin, 29(4), 830-833 (2006-04-06)
A new ursane-type triterpenoid, weigelic acid (1), and seven known compounds, ursolic acid (2), ilekudinol A (3), corosolic acid (4), ilekudinol B (5), esculentic acid (6), pomolic acid (7), and asiatic acid (8) were isolated from the leaf and stem
Studies on constituents of medicinal plants. XIII. Constituents of the pericarps of the capsules of Euscaphis japonica Pax.
K Takahashi et al.
Chemical & pharmaceutical bulletin, 22(3), 650-653 (1974-03-01)
Y Kashiwada et al.
Journal of natural products, 61(9), 1090-1095 (1998-09-28)
Oleanolic acid (1) was identified as an anti-HIV principle from several plants, including Rosa woodsii (leaves), Prosopis glandulosa (leaves and twigs), Phoradendron juniperinum (whole plant), Syzygium claviflorum (leaves), Hyptis capitata (whole plant), and Ternstromia gymnanthera (aerial part). It inhibited HIV-1

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