Skip to Content
Merck
CN
All Photos(2)

Documents

Safety Information

SMB00461

Sigma-Aldrich

Harmine hydrochloride

≥98% (HPLC)

Sign Into View Organizational & Contract Pricing
All Photos(2)
Synonym(s):
7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole hydrochloride
Empirical Formula (Hill Notation):
C13H12N2O · HCl
CAS Number:
343-27-1
Molecular Weight:
248.71
EC Number:
206-443-8
MDL number:
MFCD00012641
UNSPSC Code:
12352205
PubChem Substance ID:
329825025
NACRES:
NA.25

Quality Level

200

Assay

≥98% (HPLC)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

Cl.COc1ccc2c(c1)[nH]c3c(C)nccc23

InChI

1S/C13H12N2O.ClH/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13;/h3-7,15H,1-2H3;1H

InChI key

VNPLYCKZIUTKJM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Harmine hydrochloride is an alkaloid found in Peganum harmala.

Biochem/physiol Actions

CNS stimulant.
Harmine hydrochloride has been considered for treatment of cancer and cerebral diseases and is a known CNS stimulant.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Xiuyun Li et al.
Frontiers in microbiology, 10, 2295-2295 (2019-11-22)
Several studies have demonstrated the significant antiviral, antimicrobial, antiplasmodial, antioxidative, antifungal, antimutagenic, and antitumor properties of harmine hydrochloride (HMH). The main objective of the present study was to investigate the antifungal effects and underlying mechanisms of HMH when combined with
Stephanie F Bellmaine et al.
eLife, 6 (2017-09-09)
Genetic analysis has revealed that the dual specificity protein kinase DYRK1A has multiple roles in the development of the central nervous system. Increased DYRK1A gene dosage, such as occurs in Down syndrome, is known to affect neural progenitor cell differentiation
Michael Tarpley et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 162, 105821-105821 (2021-03-31)
DYRK1A (dual-specificity tyrosine phosphorylation-regulated kinase 1a) is highly expressed in glioma, an aggressive brain tumor, and has been proposed as a therapeutic target for cancer. In the current study, we have used an optimized and validated time-resolved fluorescence energy transfer
Elisangela G Cata-Preta et al.
Frontiers in pharmacology, 9, 561-561 (2018-06-14)
Ayahuasca is a hallucinogenic beverage produced from the decoction of Banisteriopsis caapi (Bc) and Psychotria viridis (Pv), β-carboline- and N,N-dimethyltryptamine(DMT)-containing plants, respectively. Accumulating evidence suggests that ayahuasca may have therapeutic effects on ethanol abuse. It is not known, however, whether
Ronan Le Moigne et al.
Cells, 9(5) (2020-05-14)
Numerous studies have shown that alteration of actin remodeling plays a pivotal role in the regulation of morphologic and phenotypic changes leading to malignancy. In the present study, we searched for drugs that can regulate actin polymerization and reverse the
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service