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Merck
CN

SMB00398

Cornin

≥98% (HPLC)

Synonym(s):

Verbenalin, Verbenaloside

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About This Item

Empirical Formula (Hill Notation):
C17H24O10
CAS Number:
548-37-8
Molecular Weight:
388.37
UNSPSC Code:
12352205
NACRES:
NA.25
PubChem Substance ID:
329824990
MDL number:
MFCD00017414
Beilstein/REAXYS Number:
57895

Key Documents

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Product Name

Cornin, ≥98% (HPLC)

InChI

1S/C17H24O10/c1-6-3-8(19)11-7(15(23)24-2)5-25-16(10(6)11)27-17-14(22)13(21)12(20)9(4-18)26-17/h5-6,9-14,16-18,20-22H,3-4H2,1-2H3/t6-,9+,10+,11-,12+,13-,14+,16-,17-/m0/s1

SMILES string

[H][C@@]12[C@@H](C)CC(=O)[C@]1([H])C(=CO[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)OC

InChI key

HLXRWTJXGMHOFN-XJSNKYLASA-N

assay

≥98% (HPLC)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

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Biochem/physiol Actions

Cornin is used in cardiology due to its cardioprotective property. It helps to lower blood pressure, improve heart activity, and reverse cardiac hypertrophy It can prevent lipid peroxidation catalyzed by Fe2+. Cornin can also prevent the activities of cyclooxygenase 1 (COX-1) and cyclooxygenase 1 (COX-2) enzymes. It plays a protective role against cerebral ischemia injury.

General description

Cornin is an iridoid glycoside herb. It is obtained from the fruit of Verbena Officinalis L.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL8864
SLBN0857V

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Zechun Kang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 58, 340-346 (2013-05-25)
In the present study, we sought to elucidate whether Cornin contributes to induce angiogenesis and its mechanisms. To this end, we examined the role of Cornin on human brain microvascular endothelial cell line (HBMEC) proliferation, invasion, and tube formation in
Qun Zhang et al.
BMC complementary medicine and therapies, 21(1), 138-138 (2021-05-11)
Cornin is a commonly used herb in cardiology for its cardioprotective effect. The effect of herbs on the activity of cytochrome P450 enzymes (CYP450s) can induce adverse drug-drug interaction even treatment failure. Therefore, it is necessary to investigate the effect

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