SMB00339
(-)-Tetrahydropalmatine
≥98% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C21H25NO4
CAS Number:
Molecular Weight:
355.43
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
Product Name
(-)-Tetrahydropalmatine, ≥98% (HPLC)
InChI
1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m0/s1
SMILES string
COC1=CC=C2C(CN(CCC3=C4C=C(OC)C(OC)=C3)[C@@]4([H])C2)=C1OC
InChI key
AEQDJSLRWYMAQI-KRWDZBQOSA-N
assay
≥98% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Tetrahydropalmatine is a potent muscle relaxant and has shown analgesic effects. Tetrahydropalmatine is known to help in the recovery of cocaine addiction, as it is an antagonist of dopamine (DA) D1 and D2 receptor.
General description
Tetrahydropalmatine is an tetrahydroprotoberberine isoquinoline alkaloid found primarily in the Corydalis genus.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
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Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats
Mantsch JR, et al.
Psychopharmacology, 192(4) (2007)
Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats
Xi ZX, et al.
Neuropharmacology, 53(6) (2007)
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