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SMB00112

Sigma-Aldrich

Andrographiside

≥95% (LC/MS-ELSD)

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Empirical Formula (Hill Notation):
C26H40O10
CAS Number:
82209-76-5
Molecular Weight:
512.59
UNSPSC Code:
12352205
PubChem Substance ID:
329824790
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

C[C@@]12CC[C@@H](O)[C@@](C)(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]1CCC(=C)[C@H]2C\C=C4/C[C@@H](O)OC4=O

InChI

1S/C26H40O10/c1-13-4-7-17-25(2,15(13)6-5-14-10-19(29)36-23(14)33)9-8-18(28)26(17,3)12-34-24-22(32)21(31)20(30)16(11-27)35-24/h5,15-22,24,27-32H,1,4,6-12H2,2-3H3/b14-5+/t15-,16-,17+,18-,19+,20-,21+,22-,24-,25+,26+/m1/s1

InChI key

ODNIGBWMYZIVBO-AZWZBXPUSA-N

Related Categories

General description

Andrographiside is a labdane diterpenoid glucoside found in Andrographis paniculata, which is an annual herbaceous plant traditionally used to treat infections in Southern Asia.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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[Isolation and structure of two new diterpenoid glucosides from Andrographis paniculata Nees].
C Q Hu et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 17(6), 435-440 (1982-06-01)
Jing Li et al.
Cellular & molecular immunology, 6(5), 381-385 (2009-11-06)
Andrographolide from traditional Chinese herbal medicines previously showed it possesses a strong anti-inflammatory activity. In present study, we investigated whether Andrographolide could inhibit allergen-induced airway inflammation and airways hyper-responsiveness and explored the mechanism of Andrographolide on allergen-induced airway inflammation and
[Pharmacological studies on thirteen kinds of injections from Andrographis paniculata. I. Antipyretic, anti-inflammatory effects and toxicity].
W L Deng
Zhong yao tong bao (Beijing, China : 1981), 10(7), 38-42 (1985-07-01)
[Comprehensive evaluation of cuanhuning injection].
Y Huang
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 26(6), 427-429 (2003-01-17)
J Melchior et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 7(5), 341-350 (2000-11-18)
Two randomized double-blind, placebo-controlled parallel group clinical trials were performed to investigate the effect of a standardized extract (SHA-10) of Andrographis paniculata fixed combination (Kan jang) in the treatment of uncomplicated upper-respiratory tract infections. 46 patients in the pilot study

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