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Merck
CN

SEP110

Seppro Mouse

Spin Columns

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
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Product Name

Seppro Mouse, Spin Columns

capacity

0.3 mg total protein loading(7.5 μL of mouse plasma, average mouse protein concentration 40 mg/mL)

storage temp.

2-8°C

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Application

Seppro Mouse, spin column (10μL capacity) is designed for use as a plasma/serum protein removal tool base upon avian antibody (IgY)-antigen immune affinity removal of seven highly abundant proteins (HAP) from mouse plasma protein mixtures via liquid chromatography. Seppro Mouse, spin column is used to support the analysis of low abundance mouse serum/plasma proteins.

General description

Immunoaffinity partitioning of highly-abundant proteins (HAP) has proven to be one of the most effective approaches for overcoming the wide dynamic range of plasma protein concentration, as well as enabling the detection of low-abundant proteins (LAP). Avian polyclonal IgY (Immunoglobulin Yolk) antibodies have unique and advantageous features that allow highly-specific partitioning of protein mixtures. Sigma offers a novel Seppro IgY-M7 column system, which takes you deeper into the mouse plasma/serum proteome.

Proteins Partitioned:

Mice Serum Albumin
IgG
Fibrinogen
Transferrin
IgM
Haptoglobin
alpha1-Antitrypsin

Legal Information

Seppro is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

Regulatory Information

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Egle Bytautiene et al.
American journal of obstetrics and gynecology, 208(5), 388-388 (2013-03-19)
Preeclampsia is associated with long-term adverse maternal health, such as cardiovascular and metabolic diseases. The objective of this study was to determine whether preeclampsia in a well-characterized animal model that was induced by overexpression of soluble fms-like tyrosine kinase-1 (sFlt1)

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