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Safety Information

SAB6100006

Anti-IL-12b Reference Antibody

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Synonym(s):

IL-12B, IL-12 subunit p40, CLMF p40, NKSF2, IL-12 subunit p40, CLMF p40, NKSF2

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About This Item

recombinant

expressed in CHO cells

Quality Level

100

conjugate

unconjugated

antibody product type

primary antibodies

clone

recombinant monoclonal

form

lyophilized

species reactivity

human

concentration

1 mg/mL

technique(s)

ELISA: 0.0001-10 μg/mL

optimum pH

6.2

pH range

5.5-6.10

immunogen sequence

MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRGRRASQ

Protein ID accession no.

NP_002178

UniProt accession no.

P29460

storage temp.

-65 to -96°C

target post-translational modification

unmodified

Gene Information

human ... IL12B(3593)

General description

Anti-IL-12b Reference Antibody, expressed from CHO cells with a heavy chain type of huIgG1 and a light chain type of hukappa, has a predicted MW of 145.5 kDa. This antibody serves as a versatile tool for various research applications. It enables ELISA assays for quantifying IL-12b expression levels, FACS for precise cell sorting, kinetic studies to analyze its binding properties, functional assays to assess its biological activity, and utilization in animal models to evaluate its efficacy and safety profiles in vivo. These applications provide comprehensive insights into its potential therapeutic applications, particularly in the treatment of inflammatory and autoimmune diseases.

Immunogen

IL-12β

Packaging

100ug/vial; 1mg/vial

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake it to solubilize the protein completely. Do not vortex.

Storage and Stability

Upon receipt, store immediately at -20°C for 24 months in lypholized state. -80°C for 12 months after reconstitution. Avoid repeated freeze-thaw cycles.

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Regulatory Information

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Certificates of Analysis (COA)

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