SAB5801004
Alpaca Anti-Mouse IgG(Fcγ) Biotin single domain Antibody
recombinant Alpaca(VHH) Nano antibody
Sign Into View Organizational & Contract Pricing
All Photos(2)
Recombinant Alpaca single variable domain secondary Nanobody
Recommended Products
biological source
alpaca
recombinant
expressed in E. coli
conjugate
biotin
antibody form
affinity purified immunoglobulin
antibody product type
secondary antibodies
clone
polyclonal
form
lyophilized solid
mol wt
14 kDa
species reactivity
Alpaca, mouse
technique(s)
ELISA: 1:10000-1:50000
western blot: 1:10000-1:50000
size
0.1 mL
color
colorless
isotype
VHH
shipped in
wet ice
storage temp.
2-8°C
General description
Alpaca Anti-Mouse IgG(Fcγ) Biotin single domain Antibody is designed to specifically detect mouse IgG Fcγ fragment(including mouse IgG1, IgG2a, IgG2b, IgG3). It is a single domain recombinant antibody to mouse IgG Fc coupled to Biotin. Based on immunoelectrophoresis and/or ELISA, Alpaca Anti-Mouse IgG(Fcγ) Biotin single domain Antibody reacts with the Fc fragment of mouse IgG heavy chain but not with the Fab portion of mouse IgG.
Most monoclonal antibodies are generated in mouse. There are five antibody isotypes (IgA, IgD, IgE, IgG, and IgM) from mouse. Each isotype has a different heavy chain. Mouse IgG constitutes 75% of serum immunoglobulins, and IgG is the predominant form of first antibody produced from mouse. Mouse IgG consists of five subclasses-IgG1, IgG2a, IgG2b, IgG2c(inbred mouse strains with the Igh1-b allele have IgG2c isotype instead of IgG2a), IgG3. They are highly homologous and differ mainly in the hinge region. The whole IgG molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgG contains two heavy and light chains, and the heavy chain is about 50 KD and the light chain is about 25 KD. The common IgG is monomeric with a molecular weight of approximately 150 kD.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(<15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
Most monoclonal antibodies are generated in mouse. There are five antibody isotypes (IgA, IgD, IgE, IgG, and IgM) from mouse. Each isotype has a different heavy chain. Mouse IgG constitutes 75% of serum immunoglobulins, and IgG is the predominant form of first antibody produced from mouse. Mouse IgG consists of five subclasses-IgG1, IgG2a, IgG2b, IgG2c(inbred mouse strains with the Igh1-b allele have IgG2c isotype instead of IgG2a), IgG3. They are highly homologous and differ mainly in the hinge region. The whole IgG molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgG contains two heavy and light chains, and the heavy chain is about 50 KD and the light chain is about 25 KD. The common IgG is monomeric with a molecular weight of approximately 150 kD.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(<15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
Specificity
Mouse IgG(Fcγ fragment specific)
Isotype: VHH domain of alpaca IgG2b/2c
Isotype: VHH domain of alpaca IgG2b/2c
Immunogen
Recombinant Alpaca single variable domain secondary nano antibody
Packaging
100 μg in Glass bottle
Physical form
Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose
Reconstitution
Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL
Storage and Stability
After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Stable for 12 months at -20°C
Other Notes
No cross-reactivity with mouse IgM, rabbit, human, cynomolgus, rat, goat IgG
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Skin Sens. 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service