SAB5702542
Anti-GLP-1 Antibody, clone 1R1J8, Rabbit Monoclonal
Synonym(s):
GLP-1, GLP1, GLP2, GRPP
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1R1J8, monoclonal
Application:
IF, IHC
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
material
colorless
clone
1R1J8, monoclonal
form
liquid
species reactivity
rat, mouse
concentration
0.8 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200
color
colorless
isotype
IgG
immunogen sequence
RAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGS
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GCG(2641)
General description
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human GLP-1 (P01275).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
IHC, IF/ICC
Storage Class
10 - Combustible liquids
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