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Merck
CN

SAB5702497

Anti-Peroxiredoxin 2 (PRDX2) Antibody, clone 1U9L9, Rabbit Monoclonal

Synonym(s):

HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
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technique(s)

western blot: 1:500 - 1:2000

biological source

rabbit

conjugate

unconjugated

material

colorless

clone

1U9L9, monoclonal

form

liquid

mol wt

22 kDa

species reactivity

human, rat, rat

concentration

0.50 mg/mL

color

colorless

isotype

IgG

immunogen sequence

MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLN

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PRDX2(7001)

Application

WB

General description

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Peroxiredoxin 2 (PRDX2) (PRDX2) (P32119).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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