SAB5702406
Anti-Plexin A1 Antibody, clone 2A5Z6, Rabbit Monoclonal
Synonym(s):
NOV, NOVP, PLEXIN-A1, PLXN1
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
2A5Z6, monoclonal
form
liquid
mol wt
250 kDa
species reactivity
rat, human, rat
concentration
0.7 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPT
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PLXNA1(5361)
Application
WB
General description
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Plexin A1 (Q9UIW2).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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