SAB5702404
Anti-BMP15 Antibody, clone 6K5C3, Rabbit Monoclonal
Synonym(s):
GDF9B, ODG2, POF4
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
isotype
IgG
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
6K5C3, monoclonal
form
liquid
mol wt
50 kDa
species reactivity
rat, human, rat
concentration
0.31 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
immunogen sequence
LHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BMP15(9210)
Application
WB
General description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 293-392 of human BMP15 (O95972).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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