SAB5702281
Anti-Osteocalcin (BGLAP) Antibody, clone 2T1J7, Rabbit Monoclonal
Synonym(s):
BGLAP,BGP,OC,OCN,osteocalcin
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About This Item
biological source
rabbit
Quality Level
material
colorless
clone
2T1J7, monoclonal
form
liquid
mol wt
11 kDa
species reactivity
human, rat, rat
concentration
1 mg/mL
technique(s)
western blot: 1:500 - 1:1000
color
colorless
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... BGLAP(632)
General description
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Immunogen
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of Human BGLAP.
Application
WB
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
WGK
WGK 3
Regulatory Information
常规特殊物品
含少量动物源组分生物产品
Certificates of Analysis (COA)
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