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Safety Information

SAB5702271

Sigma-Aldrich

Anti-TCF1/TCF7 Antibody, clone 4K0X6, Rabbit Monoclonal

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Synonym(s):
TCF7,TCF-1
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

100

material

colorless

clone

4K0X6, monoclonal

form

liquid

mol wt

28-50 kDa

species reactivity

human, rat, rat

concentration

1.00 mg/mL

technique(s)

western blot: 1:500 - 1:1000

color

colorless

isotype

IgG

immunogen sequence

ELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKA

UniProt accession no.

P36402

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TCF7(6932)

General description

The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TCF1/TCF7 (NP_003193.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

WGK

WGK 3

Regulatory Information

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