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Safety Information

SAB5702147

Sigma-Aldrich

Anti-GFAP Antibody, clone 8M2F9, Rabbit Monoclonal

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Synonym(s):
ALXDRD,GFAP
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

100

material

colorless

clone

8M2F9, monoclonal

form

liquid

mol wt

48 kDa

species reactivity

human, rat, rat

concentration

0.50 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAE

UniProt accession no.

P14136

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GFAP(2670)

General description

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GFAP (P14136).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

WGK

WGK 3

Regulatory Information

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