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Safety Information

SAB5702099

Sigma-Aldrich

Anti-Integrin alpha 5 (ITGA5/CD49e) Antibody, clone 8F2O6, Rabbit Monoclonal

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Synonym(s):
CD49e,FNRA,VLA-5,VLA5A,Integrin alpha 5,ITGA5
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

material

colorless

clone

8F2O6, monoclonal

form

liquid

species reactivity

human, rat, rat

concentration

0.44 mg/mL

technique(s)

flow cytometry: 1:50 - 1:200
immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

HQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLPYGTAMEKAQLKPPATSDA

UniProt accession no.

P08648

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ITGA5(3678)

General description

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 950-1049 of human Integrin alpha 5 (ITGA5/CD49e) (P08648).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC, IP, FC

WGK

WGK 1

Regulatory Information

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