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Key Documents

Safety Information

SAB5702040

Sigma-Aldrich

Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal

Synonym(s):

ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM

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5 ML
CN¥463.55

CN¥463.55

Available to ship onApril 27, 2025Details

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5 ML
CN¥463.55

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

CN¥463.55

Available to ship onApril 27, 2025Details

biological source

rabbit

Quality Level

100

material

colorless

clone

5C5N7, monoclonal

form

liquid

mol wt

58 kDa

species reactivity

human

concentration

1.75 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

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A1470

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technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

200

form

liquid

form

liquid

form

solution

form

lyophilized powder

impurities

endotoxin, tested

impurities

≤400 EU/mL endotoxin

impurities

≤0.05% fatty acid, ≤200 EU/mL endotoxin

impurities

≤20 ppm Pb, ≤3 EU/mg endotoxin

sterility

sterile-filtered

sterility

sterile-filtered

sterility

sterile-filtered

sterility

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

General description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aromatase (CYP19A1) (P11511).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Information

常规特殊物品
含少量动物源组分生物产品
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