SAB5701930
Anti-Phospho-CGAS-S291 antibody produced in rabbit
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UNSPSC Code:
12352203
NACRES:
NA.41
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biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
rat, human
concentration
0.439 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer291)
Gene Information
mouse ... CGAS(214763)
General description
The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Immunogen
A phospho synthetic peptide corresponding to residues surrounding S291 of Mouse CGAS.
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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