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Safety Information

SAB5701888

Sigma-Aldrich

Anti-Phospho-p70 S6 Kinase 1-Thr421 antibody produced in rabbit

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UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human

concentration

0.72 mg/mL

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr421)

Gene Information

human ... RPS6KB1(6198)

General description

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Immunogen

A phospho specific peptide corresponding to residues surrounding Thr421 of human RPS6KB1.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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