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Safety Information

SAB5701626

Sigma-Aldrich

Anti-KAT1/HAT1 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

100

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

mouse, rat, human

concentration

2.61 mg/mL

technique(s)

immunohistochemistry: 1:50-1:100
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

O14929

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HAT1(8520)

General description

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 245-419 of human KAT1/KAT1/HAT1 (NP_003633.1).

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

Certificates of Analysis (COA)

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