All Photos(6)
Synonym(s):
BLCPMG, OCLN, Occludin, PPP1R115, PTORCH1, occludin
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
23
31
52
54
59
8
species reactivity
human, mouse, rat
concentration
1.77 mg/ml
technique(s)
immunofluorescence: 1:50-1:100
immunohistochemistry: 1:50-1:200
western blot: 1:1000-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... OCLN(100506658)
General description
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human Occludin (NP_002529.1).
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃. Avoid freeze / thaw cycles.
WGK
WGK 1
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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