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Safety Information

SAB5700367

Sigma-Aldrich

Anti-Phospho-YAP1-S127 antibody produced in rabbit

Synonym(s):

COB1, YAP, YAP1, YAP2, YAP65, YKI

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

36
 48
 49
 50
 52
 53
 54

species reactivity

mouse, human, rat

concentration

0.56 mg/ml

technique(s)

immunofluorescence: 1:20-1:100
western blot: 1:500-1:1000

UniProt accession no.

P46937

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer127)

Gene Information

human ... YAP1(10413)

General description

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen

A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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